Capecitabine (Xeloda)

Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

Grouped product items
Product Name Price Stock Qty
Capecitabine 1g
$40.00
In stock
Capecitabine 5g
$160.00
In stock
Capecitabine (Xeloda) 10mM * 1mL in DMSO
$59.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Capecitabine (Xeloda) has been cited by 3 publications
  • Takashi Azuma, .et al. , SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
  • Biological Activity
    Discription

    Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

    Targets
    Target Value
    Product Information
    Catalog Num A10177
    Formula C15H22FN3O6
    Molecular Weight 359.4
    CAS Number 154361-50-9
    SMILES CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O
    Synonyms Captabin
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 62 mg/mL (172.53 mM)
    Water 5 mg/mL (13.91 mM)
    Ethanol 62 mg/mL (172.53 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.82 mL 139.12 mL 278.24 mL
    0.5 mM 5.56 mL 27.82 mL 55.65 mL
    1 mM 2.78 mL 13.91 mL 27.82 mL
    5 mM 0.56 mL 2.78 mL 5.56 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Capecitabine (Xeloda) | Capecitabine (Xeloda) Supplier | purchase Capecitabine (Xeloda) | Capecitabine (Xeloda) cost | Capecitabine (Xeloda) manufacturer | order Capecitabine (Xeloda) | Capecitabine (Xeloda) distributor | buy 154361-50-9 | 154361-50-9 Supplier | purchase 154361-50-9 | 154361-50-9 cost | 154361-50-9 manufacturer | order 154361-50-9 | 154361-50-9 distributor