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CL-387785 (EKI-785)

EGFR inhibitor

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Catalog No. A13146

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CL-387785 10mg A13146-10
$120.00
CL-387785 25mg A13146-25
$250.00
CL-387785 50mg A13146-50
$450.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.

CL-387785 (EKI-785)

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Chemical Information

Catalog Num A13146
Actions Inhibitor
M. Wt 381.23
Formula C18H13BrN4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 194423-06-8
Synonyms WAY-EKI 785, CL387785, CL 387785, EKI785, WAY-EKI785, EKI 785, EKI-785
SMILES code CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1
Chemical Name (Z)-N-(4-((3-bromophenyl)amino)quinazolin-6-yl)but-2-ynimidic acid

Biological Activity

Description
CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Targets
EGFR
370 pM

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