CUDC-305 (DEBIO-0932 )

HSP90 inhibitor

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Catalog No. A12648

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CUDC-305 (DEBIO-0932 ) 5mg A12648-5
$110.00
CUDC-305 (DEBIO-0932 ) 10mg A12648-10
$170.00
CUDC-305 (DEBIO-0932 ) 25mg A12648-25
$350.00
CUDC-305 (DEBIO-0932 ) 50mg A12648-50
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.

CUDC-305 (DEBIO-0932 )

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Chemical Information

Catalog Num A12648
Actions Inhibitor
M. Wt 442.58
Formula C22H30N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1061318-81-7
Synonyms Debio0932; CUDC305
SMILES code CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4
Chemical Name 2-((6-(dimethylamino)benzo[d][1,3]dioxol-5-yl)thio)-1-(2-(neopentylamino)ethyl)-1H-imidazo[4,5-c]pyridin-4-amine

Biological Activity

Description
Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.

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