Dabrafenib Mesylate

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Raf inhibitor

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Catalog No. A15059

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Dabrafenib Mesylate 10mg A15059-10

Regular Price: $70.00

Special Price: $56.00

Dabrafenib Mesylate 50mg A15059-50

Regular Price: $150.00

Special Price: $120.00

Dabrafenib Mesylate 100mg A15059-100

Regular Price: $240.00

Special Price: $192.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Dabrafenib Mesylate is a novel, potent, and selective Raf kinase inhibitor that is capableof inhibiting the kinase activity of wild-type B-Raf, B-RafV600Eand c-Raf with IC50 values of 3.2, 0.8, and 5.0 nM, respectively.

Dabrafenib Mesylate

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Chemical Information

Catalog Num A15059
Actions Inhibitor
M. Wt 615.67
Formula C24H24F3N5O5S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1195768-06-9
Synonyms GSK-2118436 Mesylate, GSK2118436 Mesylate, GSK 2118436 Mesylate, GSK 2118436B
SMILES code CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O
Chemical Name N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;methanesulfonic acid

Biological Activity

Description
Dabrafenib Mesylate is a novel, potent, and selective Raf kinase inhibitor that is capableof inhibiting the kinase activity of wild-type B-Raf, B-RafV600Eand c-Raf with IC50 values of 3.2, 0.8, and 5.0 nM, respectively.

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