Deferasirox

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Iron chelator

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Catalog No. A10293

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Deferasirox 5mg A10293-5

Regular Price: $50.00

Special Price: $42.50

Deferasirox 10mg A10293-10

Regular Price: $90.00

Special Price: $76.50

Deferasirox 25mg A10293-25

Regular Price: $180.00

Special Price: $153.00

Deferasirox 50mg A10293-50

Regular Price: $320.00

Special Price: $272.00

Deferasirox 10mM * 1mL in DMSO A10293-10mM-D

Regular Price: $96.00

Special Price: $81.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.

Deferasirox

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Chemical Information

Catalog Num A10293
Actions No
M. Wt 373.36
Formula C21H15N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 201530-41-8
Synonyms ICL-670, ICL-670A, CGP-72670
SMILES code C1=C/C(=C\2/N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1
Chemical Name [4-[(3Z,5E)-3,5-bis(6-oxo-1-cyclohexa-2,4-dienylidene)-1,2,4-triazolidin-1-yl]benzoic acid

Biological Activity

Description
Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.

Solubility

Solubility (25°C) * In vitro DMSO 74 mg/mL (198.2 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (5.35 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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