Deforolimus (Ridaforolimus)

Catalog No.: A10295
mTOR Inhibitor

Deforolimus (Ridaforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.

Grouped product items
Product Name Price Stock Qty
Deforolimus 5mg
$55.00
In stock
Deforolimus 10mg
$77.00
In stock
Deforolimus 50mg
$296.00
In stock
Deforolimus 100mg
$500.00
In stock
Deforolimus (Ridaforolimus) 10mM * 1mL in DMSO
$178.00
In stock
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Biological Activity
Discription

Deforolimus (Ridaforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.

Targets
Target Value
Product Information
Catalog Num A10295
Formula C53H84NO14P
Molecular Weight 990.2
CAS Number 572924-54-0
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC
Synonyms AP23573, MK-8669
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 196 mg/mL (197.93 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% H2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.1 mL 50.49 mL 100.99 mL
0.5 mM 2.02 mL 10.1 mL 20.2 mL
1 mM 1.01 mL 5.05 mL 10.1 mL
5 mM 0.2 mL 1.01 mL 2.02 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
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