E-4031 dihydrochloride

Catalog No.: A12857
K+ channel blocker?€?
E-4031 dihydrochloride is a selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr).
Grouped product items
Product Name Price Stock Qty
E-4031 dihydrochloride 10mg
$105.00
In stock
E-4031 dihydrochloride 25mg
$240.00
In stock
E-4031 dihydrochloride 50mg
$450.00
In stock
E-4031 dihydrochloride 100mg
$850.00
In stock
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Biological Activity
Discription E-4031 dihydrochloride is a selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr).
Product Information
Catalog Num A12857
Formula C21H27N3O3S.2HCl
Molecular Weight 474.44
CAS Number 113559-13-0
SMILES CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl
Synonyms E4031, E 4031
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 28 mg/mL (59.01 mM)
Water 44 mg/mL (92.74 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.08 mL 105.39 mL 210.77 mL
0.5 mM 4.22 mL 21.08 mL 42.15 mL
1 mM 2.11 mL 10.54 mL 21.08 mL
5 mM 0.42 mL 2.11 mL 4.22 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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