FABP4 Inhibitor

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Catalog No. A13404

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
FABP4 Inhibitor 5mg A13404-5

Regular Price: $80.00

Special Price: $64.00

FABP4 Inhibitor 10mg A13404-10

Regular Price: $140.00

Special Price: $112.00

FABP4 Inhibitor 25mg A13404-25

Regular Price: $280.00

Special Price: $224.00

FABP4 Inhibitor 50mg A13404-50

Regular Price: $500.00

Special Price: $400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

FABP4 Inhibitor is a cell-permeable biphenylazolo-oxyacetate that acts as a potent and selective inhibitor of adipocyte Fatty-Acid-Binding Protein (aFABP/aP2) by targeting its fatty acid-binding pocket (Ki = < 2 nM in a competitive binding assay using 1,8-ANS), while exhibiting much lower affinity for muscle and epidermal FABP's (Ki = 250 nM and 350 nM, respectively).

FABP4 Inhibitor

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Chemical Information

Catalog Num A13404
Actions N/A
M. Wt 474.55
Formula C31H26N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 300657-03-8
Synonyms N/A
SMILES code CCC1=C(C(=NN1C2=CC=CC=C2C3=CC(=CC=C3)OCC(=O)O)C4=CC=CC=C4)C5=CC=CC=C5
Chemical Name 2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]acetic acid

Biological Activity

Description
FABP4 Inhibitor is a cell-permeable biphenylazolo-oxyacetate that acts as a potent and selective inhibitor of adipocyte Fatty-Acid-Binding Protein (aFABP/aP2) by targeting its fatty acid-binding pocket (Ki = < 2 nM in a competitive binding assay using 1,8-ANS), while exhibiting much lower affinity for muscle and epidermal FABP's (Ki = 250 nM and 350 nM, respectively).

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