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GNE0877

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LRRK2 inhibitor

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Catalog No. A13969

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GNE0877 5mg A13969-5

Regular Price: $160.00

Special Price: $144.00

GNE0877 10mg A13969-10

Regular Price: $280.00

Special Price: $252.00

GNE0877 25mg A13969-25

Regular Price: $550.00

Special Price: $495.00

GNE0877 10mM * 1mL in DMSO A13969-10mM-D

Regular Price: $195.00

Special Price: $175.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GNE-0877 is a highly potent and selective LRRK2 inhibitor.

GNE0877

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Chemical Information

Catalog Num A13969
Actions Inhibitor
M. Wt 339.31895
Formula C14H16F3N7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1374828-69-9
Synonyms GNE-0877, GNE 0877, GNE0877
SMILES code CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N
Chemical Name 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile

Biological Activity

Description
GNE-0877 is a highly potent and selective LRRK2 inhibitor.
Targets
LRRK2
0.7 nM(Ki)

Solubility

Solubility (25°C)* In vitro DMSO 67 mg/mL (197.45 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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