GSK-650394

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SGK1 inhibitor

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Catalog No. A13309

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK-650394 10mg A13309-10

Regular Price: $120.00

Special Price: $96.00

GSK-650394 25mg A13309-25

Regular Price: $250.00

Special Price: $200.00

GSK-650394 50mg A13309-50

Regular Price: $400.00

Special Price: $320.00

GSK-650394 10mM * 1mL in DMSO A13309-10mM-D

Regular Price: $105.00

Special Price: $84.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK 650394 is a glucocorticoid- and serum-regulated kinase 1 (SGK1) inhibitor which displays antiproliferative properties against the LNCaP prostate carcinoma cell line.

GSK-650394

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Chemical Information

Catalog Num A13309
Actions Inhibitor
M. Wt 382.45
Formula C25H22N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 890842-28-1
Synonyms GSK 650394, GSK650394
SMILES code C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O
Chemical Name 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoic acid

Biological Activity

Description
GSK 650394 is a glucocorticoid- and serum-regulated kinase 1 (SGK1) inhibitor which displays antiproliferative properties against the LNCaP prostate carcinoma cell line.
Targets
SGK1 SGK2
62 nM103 nM

Solubility

Solubility (25°C)* In vitro DMSO 76 mg/mL (198.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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