GSK-923295

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CENP-E inhibitor

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Catalog No. A11435

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK-923295 5mg A11435-5

Regular Price: $100.00

Special Price: $80.00

GSK-923295 10mg A11435-10

Regular Price: $170.00

Special Price: $136.00

GSK-923295 25mg A11435-25

Regular Price: $340.00

Special Price: $272.00

GSK-923295 50mg A11435-50

Regular Price: $620.00

Special Price: $496.00

GSK-923295 10mM * 1mL in DMSO A11435-10mM-D

Regular Price: $189.00

Special Price: $151.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK-923295, is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E, (CENP-E).

GSK-923295

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Chemical Information

Catalog Num A11435
Actions Inhibitor
M. Wt 592.13
Formula C32H38ClN5O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1088965-37-0
Synonyms GSK923295, GSK 923295
SMILES code C[C@@H](C1=CC=CN2C1=NC(=C2)C3=CC=C(C=C3)C[C@@H](CNC(=O)CN(C)C)NC(=O)C4=CC(=C(C=C4)OC(C)C)Cl)O
Chemical Name 3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide

Biological Activity

Description
GSK-923295, is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E, (CENP-E).
Targets
CENP-E
3.2 nM(Ki)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (168.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (168.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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