GW3965 HCl ON SALE LXR-like receptors agonist

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Catalog No. A11204

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW3965 HCl 5mg A11204-5

Regular Price: $80.00

Special Price: $68.00

GW3965 HCl 10mg A11204-10

Regular Price: $120.00

Special Price: $102.00

GW3965 HCl 50mg A11204-50

Regular Price: $470.00

Special Price: $399.50

GW3965 HCl 100mg A11204-100

Regular Price: $820.00

Special Price: $697.00

GW3965 HCl 10mM * 1mL in DMSO A11204-10mM-D

Regular Price: $158.00

Special Price: $134.30

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist.

GW3965 HCl

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Chemical Information

Catalog Num A11204
Actions Agonist
M. Wt 618.51
Formula C33H31ClF3NO3.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 405911-17-3
Synonyms GW-3965
SMILES code C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl
Chemical Name (3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-amino]-propoxy}-phenyl)-acetic acid hydrochloride

Biological Activity

GW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist.
hLXRβ (Cell-free assay) LXRα/SRC1?LiSA (Cell-free assay) hLXRα (Cell-free assay)
30 nM(EC50)125 nM(EC50)190 nM(EC50)


Solubility (25°C)* In vitro DMSO 124 mg/mL (200.48 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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