GYKI-52466 dihydrochloride AMPA and Kainate antagonist

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Catalog No. A10444

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GYKI-52466 dihydrochloride 10mg A10444-10
$80.00
GYKI-52466 dihydrochloride 25mg A10444-25
$160.00
GYKI-52466 dihydrochloride 50mg A10444-50
$300.00
GYKI-52466 dihydrochloride 100mg A10444-100
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GYKI-52466 dihydrochloride is selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively).

GYKI-52466 dihydrochloride

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Chemical Information

Catalog Num A10444
Actions Antagonist
M. Wt 366.24
Formula C17H15N3O2.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 102771-26-6
Synonyms GYKI52466, GYKI 52466
SMILES code CC1=NN=C(C2=CC3=C(C=C2C1)OCO3)C4=CC=C(C=C4)N
Chemical Name 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2?,3]benzodiazepin-5-yl)-benzenamine dihydrochloride

Biological Activity

Description
GYKI-52466 dihydrochloride is selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively).

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