HSP-990
HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's HSP-990 has been cited by 1 publications
- Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
Biological Activity
| Description | HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A12850 |
|---|---|
| Formula | C20H18FN5O2 |
| Molecular Weight | 379.39 |
| CAS Number | 934343-74-5 |
| SMILES | CC1=NC(=NC2=C1C(=O)N[C@H](C2)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC)N |
| Synonyms | HSP990, HSP 990, NVP-HSP990 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 65 mg/mL (171.32 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.36 mL | 131.79 mL | 263.58 mL |
| 0.5 mM | 5.27 mL | 26.36 mL | 52.72 mL |
| 1 mM | 2.64 mL | 13.18 mL | 26.36 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.27 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
