Istradefylline (KW-6002) ON SALE A2A antagonist

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Catalog No. A11451

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Istradefylline 5mg A11451-5

Regular Price: $70.00

Special Price: $59.50

Istradefylline 10mg A11451-10

Regular Price: $120.00

Special Price: $102.00

Istradefylline 25mg A11451-25

Regular Price: $240.00

Special Price: $204.00

Istradefylline 50mg A11451-50

Regular Price: $380.00

Special Price: $323.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been found to be useful in the treatment of Parkinson's disease.

Istradefylline (KW-6002)

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Chemical Information

Catalog Num A11451
Actions Antagonist
M. Wt 384.4
Formula C20H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 155270-99-8
Synonyms KW-6002,KW6002
SMILES code CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)OC)C
Chemical Name 8-[(E)-2-(3,4-dimethoxyphenyl)vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione

Biological Activity

Description
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been found to be useful in the treatment of Parkinson's disease.
Targets
Adenosine A2A receptor
2.2 nM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 6 mg/mL (15.6 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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