IWP-2

Catalog No.: A12707
Wnt inhibitor
IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent.
Grouped product items
Product Name Price Stock Qty
IWP-2 5mg
$50.00
In stock
IWP-2 10mg
$80.00
In stock
IWP-2 25mg
$150.00
In stock
IWP-2 100mg
$450.00
In stock
IWP-2 10mM * 1mL in DMSO
$90.00
In stock
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Biological Activity
Discription IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent.
Targets
Target Value
Product Information
Catalog Num A12707
Formula C22H18N4O2S3
Molecular Weight 466.6
CAS Number 686770-61-6
SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4
Synonyms IWP 2,IWP2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Insoluble
Water Insoluble
Ethanol DMF: 24mg/mL (51.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.43 mL 107.16 mL 214.32 mL
0.5 mM 4.29 mL 21.43 mL 42.86 mL
1 mM 2.14 mL 10.72 mL 21.43 mL
5 mM 0.43 mL 2.14 mL 4.29 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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