JIB-04

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Histone Demethylase inhibitor

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Catalog No. A13806

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JIB-04 25mg A13806-25

Regular Price: $120.00

Special Price: $102.00

JIB-04 50mg A13806-50

Regular Price: $200.00

Special Price: $170.00

JIB-04 100mg A13806-100

Regular Price: $350.00

Special Price: $297.50

JIB-04 10mM * 1mL in DMSO A13806-10mM-D

Regular Price: $90.00

Special Price: $76.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.

JIB-04

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Chemical Information

Catalog Num A13806
Actions No
M. Wt 308.76
Formula C17H13ClN4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 199596-05-9
Synonyms NSC 693627, JIB04
SMILES code C1=CC=C(C=C1)/C(=N\NC2=NC=C(C=C2)Cl)/C3=CC=CC=N3
Chemical Name 5-Chloro-2-[(E)-2-[phenyl(pyridin-2?-yl)methylidene]hydrazin-1-yl]pyridine

Biological Activity

Description
JIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.

Solubility

Solubility (25°C)* In vitro DMSO 25 mg/mL heating (80.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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