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JNJ-10397049

OX2 receptor antagonist

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Catalog No. A14104

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JNJ-10397049 10mg A14104-10
$90.00
JNJ-10397049 25mg A14104-25
$200.00
JNJ-10397049 50mg A14104-50
$300.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 ?M for OX1R).

JNJ-10397049

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Chemical Information

Catalog Num A14104
Actions Antagonist
M. Wt 484.2
Formula C19H20Br2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 708275-58-5
Synonyms JNJ 10397049, JNJ10397049
SMILES code CC1(OC[[email protected]@H]([[email protected]@H](O1)C2=CC=CC=C2)NC(=O)NC3=C(C=C(C=C3)Br)Br)C
Chemical Name N-?(2,?4-?dibromophenyl)-?N'-?[(4S,?5S)-?2,?2-?dimethyl-?4-?phenyl-?1,?3-?dioxan-?5-?yl]-?urea

Biological Activity

Description
JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 ?M for OX1R).

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