JNJ7777120

Catalog No.: A12713
Histamine Antagonist
JNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
Grouped product items
Size Price Stock Qty
5mg
$55.00
In stock
10mg
$80.00
In stock
25mg
$165.00
In stock
50mg
$280.00
In stock
100mg
$455.00
In stock
500mg
$980.00
In stock
10mM * 1mL in DMSO
$60.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's JNJ7777120 has been cited by 2 publications
  • K Yamamoto, .et al. , Naunyn-Schmiedeberg's Arch Pharmacol, 2019, pp 1-12 PMID: 30919010
  • Yamamoto K, .et al. , Neurosci Lett, 2018, May 29;676:103-107 PMID: 29655943
Biological Activity
DescriptionJNJ7777120 is a potent, selective non-imidazole H4?histamine receptor antagonist.
Targets
TargetValue
Product Information
Catalog NumA12713
FormulaC14H16N3OCl
Molecular Weight277.75
CAS Number459168-41-3
SMILESCN1CCN(CC1)C(=O)C2=CC3=C(N2)C=CC(=C3)Cl
SynonymsJNJ 7777120, JNJ-7777120
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO49 mg/mL (176.42 mM)
WaterInsoluble
Ethanol7 mg/mL (25.2 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM36 mL180.02 mL360.04 mL
0.5 mM7.2 mL36 mL72.01 mL
1 mM3.6 mL18 mL36 mL
5 mM0.72 mL3.6 mL7.2 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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