MK-1775

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WEE1 Inhibitor

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Catalog No. A10599

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-1775 5mg A10599-5

Regular Price: $70.00

Special Price: $56.00

MK-1775 10mg A10599-10

Regular Price: $90.00

Special Price: $72.00

MK-1775 25mg A10599-25

Regular Price: $140.00

Special Price: $112.00

MK-1775 50mg A10599-50

Regular Price: $250.00

Special Price: $200.00

MK-1775 10mM * 1mL in DMSO A10599-10mM-D

Regular Price: $70.00

Special Price: $56.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.

MK-1775

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Chemical Information

Catalog Num A10599
Actions Inhibitor
M. Wt 500.6
Formula C27H32N8O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 955365-80-7
Synonyms MK1775,MK 1775
SMILES code CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
Chemical Name 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one

Biological Activity

Description
MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.
Targets
Wee1 (Cell-free assay)
5.2 nM

Solubility

Solubility (25°C) * In vitro DMSO 80 mg/mL (159.8 mM)
Water 0.0001 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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