MK-3207

CGRP Receptor antagonist

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Catalog No. A15165

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-3207 10mg A15165-10
$200.00
MK-3207 25mg A15165-25
$380.00
MK-3207 50mg A15165-50
$650.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.

MK-3207

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Chemical Information

Catalog Num A15165
Actions Antagonist
M. Wt 557.59
Formula C31H29F2N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 957118-49-9
Synonyms MK3207, MK 3207
SMILES code C1CCC2(C1)C(=O)N(C(CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(CC6(C5)C7=C(NC6=O)N=CC=C7)C=C4
Chemical Name (8R)-8-(3,5-Difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide

Biological Activity

Description
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.

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