MKT 077

Catalog No.: A12388
HSP70 Inhibitor
Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.
Grouped product items
Product Name Price Stock Qty
MKT 077 5mg
$100.00
In stock
MKT 077 10mg
$180.00
In stock
MKT 077 25mg
$350.00
In stock
MKT 077 100mg
$620.00
In stock
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Biological Activity
Discription Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.
Targets
Target Value
Product Information
Catalog Num A12388
Formula C21H22ClN3OS2
Molecular Weight 432
CAS Number 147366-41-4
SMILES CCN1/C(=C/C2=CC=CC=[N+]2CC)/S/C(=C/3\N(C4=CC=CC=C4S3)C)/C1=O.[Cl-]
Synonyms MKT077, MKT-077
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 11 mg/mL (25.46 mM)
Water 75 mg/mL (173.61 mM)
Ethanol 9 mg/mL (20.83 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.15 mL 115.74 mL 231.48 mL
0.5 mM 4.63 mL 23.15 mL 46.3 mL
1 mM 2.31 mL 11.57 mL 23.15 mL
5 mM 0.46 mL 2.31 mL 4.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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