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MKT 077

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HSP70 Inhibitor

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Catalog No. A12388

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MKT 077 5mg A12388-5

Regular Price: $60.00

Special Price: $54.00

MKT 077 10mg A12388-10

Regular Price: $120.00

Special Price: $108.00

MKT 077 25mg A12388-25

Regular Price: $200.00

Special Price: $180.00

MKT 077 100mg A12388-100

Regular Price: $350.00

Special Price: $315.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.

MKT 077

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Chemical Information

Catalog Num A12388
Actions Inhibitor
M. Wt 432
Formula C21H22ClN3OS2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 147366-41-4
Synonyms MKT077, MKT-077
SMILES code CCN1/C(=C/C2=CC=CC=[N+]2CC)/S/C(=C/3\N(C4=CC=CC=C4S3)C)/C1=O.[Cl-]
Chemical Name 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3?H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene?]methyl]-pyridinium chloride

Biological Activity

Description
Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.

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