Monastrol

Kinesin-5(KIF11) inhibitor

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Catalog No. A11976

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Monastrol 5mg A11976-5
$80.00
Monastrol 10mg A11976-10
$110.00
Monastrol 25mg A11976-25
$230.00
Monastrol 50mg A11976-50
$390.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 ?M) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.

Monastrol

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Chemical Information

Catalog Num A11976
Actions Inhibitor
M. Wt 292.4
Formula C14H16N2O3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 329689-23-8
Synonyms N/A
SMILES code CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Chemical Name 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester

Biological Activity

Description
Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 ?M) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.

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