Nebivolol HCl

Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).
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Nebivolol HCl 10mg
$50.00
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Nebivolol HCl 25mg
$75.00
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Nebivolol HCl 50mg
$120.00
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Nebivolol HCl 100mg
$200.00
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Nebivolol HCl 10mM * 1mL in DMSO
$55.00
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Adooq Products cited in reputable paper
Adooq's Nebivolol HCl has been cited by 1 publications
  • Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
  • Biological Activity
    Discription Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A10630
    Formula C22H25F2NO4.HCl
    Molecular Weight 441.9
    CAS Number 152520-56-4
    SMILES C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl
    Synonyms R-67145
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 81 mg/mL (183.3 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.63 mL 113.15 mL 226.3 mL
    0.5 mM 4.53 mL 22.63 mL 45.26 mL
    1 mM 2.26 mL 11.31 mL 22.63 mL
    5 mM 0.45 mL 2.26 mL 4.53 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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