Nepicastat HCl

Nepicastat hydrochloride is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

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Product Name Price Stock Qty
Nepicastat hydrochloride 5mg
$60.00
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Nepicastat hydrochloride 10mg
$100.00
In stock
Nepicastat hydrochloride 50mg
$300.00
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Nepicastat hydrochloride 100mg
$500.00
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Nepicastat HCl 10mM * 1mL in DMSO
$99.00
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Adooq Products cited in reputable paper
Adooq's Nepicastat HCl has been cited by 1 publications
  • Melina C Acosta, .et al. , Horm Behav, 2022, Jan;137:105086 PMID: 34808463
  • Biological Activity
    Discription

    Nepicastat hydrochloride is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

    Targets
    Target Value
    Product Information
    Catalog Num A11172
    Formula C14H15F2N3S.HCl
    Molecular Weight 331.81
    CAS Number 170151-24-3
    SMILES C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F.Cl
    Synonyms RS-25560-197, SYN117
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 59 mg/mL (177.8 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% CMC Na 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.14 mL 150.69 mL 301.38 mL
    0.5 mM 6.03 mL 30.14 mL 60.28 mL
    1 mM 3.01 mL 15.07 mL 30.14 mL
    5 mM 0.6 mL 3.01 mL 6.03 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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