Norfluoxetine

serotonin uptake inhibitor

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Catalog No. A13458

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Norfluoxetine 5mg A13458-5
$120.00
Norfluoxetine 10mg A13458-10
$200.00
Norfluoxetine 25mg A13458-25
$420.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Norfluoxetine is an active metabolite of the antidepressant fluoxetine that inhibits serotonin uptake with a pKi value of 7.35.1 The S-enantiomer of norfluoxetine has 20-times higher serotonin reuptake blocking potency than the R-enantiomer (pKis = 7.86 versus 6.51, respectively).

Norfluoxetine

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Chemical Information

Catalog Num A13458
Actions Inhibitor
M. Wt 331.76
Formula C16H17ClF3NO
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 83891-03-6
Synonyms Desmethylfluoxetine
SMILES code NCCC(C1=CC=CC=C1)?OC2=CC=C(C(F)?(F)?F)?C=C2
Chemical Name γ-[4-(trifluoromethyl)phenoxy]-benzenepropanamine

Biological Activity

Description
Norfluoxetine is an active metabolite of the antidepressant fluoxetine that inhibits serotonin uptake with a pKi value of 7.35.1 The S-enantiomer of norfluoxetine has 20-times higher serotonin reuptake blocking potency than the R-enantiomer (pKis = 7.86 versus 6.51, respectively).

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