NSC 23766

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Rac1 activation inhibitor

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Catalog No. A12546

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NSC 23766 10mg A12546-10

Regular Price: $80.00

Special Price: $64.00

NSC 23766 25mg A12546-25

Regular Price: $150.00

Special Price: $120.00

NSC 23766 50mg A12546-50

Regular Price: $250.00

Special Price: $200.00

NSC 23766 100mg A12546-100

Regular Price: $400.00

Special Price: $320.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 ??M) without affecting Cdc42 or RhoA activation.

NSC 23766

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Chemical Information

Catalog Num A12546
Actions Inhibitor
M. Wt 530.97
Formula C24H35N7.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 733767-34-5
Synonyms NSC-23766, NSC23766
SMILES code CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl
Chemical Name N6-[2-[[4-(Diethylamino)-1-methylbu?tyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-qu?inolinediamine trihydrochloride

Biological Activity

Description
NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 ??M) without affecting Cdc42 or RhoA activation.

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