NVP-BGJ398 phosphate

Catalog No.: A15194
FGFR Inhibitor
NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.
Grouped product items
Product Name Price Stock Qty
NVP-BGJ398 phosphate 5mg
$60.00
In stock
NVP-BGJ398 phosphate 10mg
$90.00
In stock
NVP-BGJ398 phosphate 50mg
$240.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.
Targets
Target Value
Product Information
Catalog Num A15194
Formula C26H34Cl2N7O7P
Molecular Weight 658.47
CAS Number 1310746-10-1
SMILES CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl.OP(=O)(O)O
Synonyms BGJ-398 phosphate, BGJ 398 phosphate, NVP BGJ398 phosphate
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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