Olmesartan medoxomil

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Catalog No. A11615

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Olmesartan medoxomil 25mg A11615-25
$50.00
Olmesartan medoxomil 50mg A11615-50
$70.00
Olmesartan medoxomil 100mg A11615-100
$121.00
Olmesartan medoxomil 200mg A11615-200
$200.00
Olmesartan medoxomil 10mM * 1mL in DMSO A11615-10mM-D
$55.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.

Olmesartan medoxomil

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Chemical Information

Catalog Num A11615
Actions N/A
M. Wt 558.6
Formula C29H30N6O6
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 144689-63-4
Synonyms Benicar, Olmetec
SMILES code CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O
Chemical Name (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate

Biological Activity

Description
Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.
Targets
AT1 receptor

Solubility

Solubility (25°C)* In vitro DMSO 89 mg/mL (159.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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