OSU-03012

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PDK-1 inhibitor

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Catalog No. A10681

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
OSU-03012 5mg A10681-5
$50.00
OSU-03012 25mg A10681-25
$160.00
OSU-03012 50mg A10681-50
$300.00
OSU-03012 100mg A10681-100
$470.00
OSU-03012 10mM * 1mL in DMSO A10681-10mM-D
$90.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.

OSU-03012

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Chemical Information

Catalog Num A10681
Actions Inhibitor
M. Wt 460.2
Formula C26H19F3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 742112-33-0
Synonyms N/AAR-12, OSU03012
SMILES code C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
Chemical Name 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide

Biological Activity

Description
OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.
Targets
PDK-1 (Cell-free assay)
5 μM

Solubility

Solubility (25°C) * In vitro DMSO 11 mg/mL (23.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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