PF-04880594

RAF inhibitor

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Catalog No. A12739

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PF-04880594 5mg A12739-5
$350.00
PF-04880594 10mg A12739-10
$650.00
PF-04880594 25mg A12739-25
$1,200.00
PF-04880594 50mg A12739-50
$2,000.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.

PF-04880594

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Chemical Information

Catalog Num A12739
Actions Inhibitor
M. Wt 394.38
Formula C19H16F2N8
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1111636-35-1
Synonyms PF-04880594, PF04880594, PF 04880594
SMILES code C1=CNC2=NC=C(C=C21)C3=NN(C=C3C4=NC(=NC=C4)NCCC#N)CC(F)F
Chemical Name 3-((4-(1-(2,2-difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propanenitrile

Biological Activity

Description
PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.

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