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|Storage||at -20°C 2 years|
|SMILES code||O=C1N(Cc2c(N1C)nc(n[c-]2)Nc1[c-]c(nn1C)C)c1[c-]c([c-][c-]c1C)NC(=O)c1[c-][c -][c-]c([c-]1)C(F)(F)F|
|Chemical Name||N-[3-[7-[(1,3-Dimethyl-1H-pyrazol-5 -yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5- d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoro methyl)benzamide|
|The activity of Pluripotin (SC-1) is mediated by the combined inhibition of RasGAP and ERK1 with Kd values of 98 and 212 nM, respectively.|
|A10255||ABT-737||<1 mg/mL||163 mg/mL||<1 mg/mL|
|A10022||ABT-263 (Navitoclax)||<1 mg/mL||195 mg/mL||<1 mg/mL|
|A10665||Obatoclax mesylate (GX15-070)||<1 mg/mL||83 mg/mL||<1 mg/mL|
|A10955||TW-37||<1 mg/mL||115 mg/mL||4 mg/mL|
|A10984||VX-765||<1 mg/mL||102 mg/mL||102 mg/mL|
|A11090||PAC-1||<1 mg/mL||78 mg/mL||16 mg/mL|
|A10491||JNJ 26854165||<1 mg/mL||66 mg/mL||2 mg/mL|
|A11931||RITA (NSC 652287)||<1 mg/mL||115 mg/mL||4 mg/mL|
|A10522||Lenalidomide (CC-5013)||<1 mg/mL||52 mg/mL||<1 mg/mL|
|A10743||Pomalidomide (CC-4047)||<1 mg/mL||55 mg/mL||<1 mg/mL|
|A11163||AT-406||<1 mg/mL||112 mg/mL||112 mg/mL|
|A11002||YM155||89 mg/mL||55 mg/mL||6 mg/mL|
|A10935||Tipifarnib (Zarnestra)||<1 mg/mL||83 mg/mL||<1 mg/mL|
|A10657||Nutlin-3||<1 mg/mL||116 mg/mL||116 mg/mL|
|A11635||Cyclophosphamide monohydrate||20 mg/mL||56 mg/mL||<1 mg/mL|
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Tipifarnib (Zarnestra) is a farnesyltransferase inhibitor that inhibits the Ras kinase in a post translational modification step before the kinase pathway becomes hyperactive. ...
Starting at: $150.00
PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth. ...
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Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. ...
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MDM2 antagonist nutlin-3 is a potent inducer of apoptosis. ...
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