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PLX4032 (Vemurafenib)

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Catalog No. A10739
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Availability: In stock

Product Name Catalog No. Price Qty
PLX4032 10mg A10739-10

Regular Price: $40.00

Special Price: $32.00

PLX4032 50mg A10739-50

Regular Price: $138.00

Special Price: $110.40

PLX4032 100mg A10739-100

Regular Price: $220.00

Special Price: $176.00

PLX4032 200mg A10739-200

Regular Price: $400.00

Special Price: $320.00

PLX4032 10mM * 1mL in DMSO A10739-10mM-D

Regular Price: $79.00

Special Price: $63.20

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.

PLX4032 (Vemurafenib)

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Chemical Information

Catalog Num A10739
M. Wt 489.9
Formula C23H18ClF2N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 918504-65-1
Synonyms RG7204,RO5185426,Zelboraf, PLX-4032
SMILES code CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)Cl)F
Chemical Name N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

Biological Activity

Description PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.
Targets
IC50

Solubility

Solubility (25°C) * In vitro DMSO 98 mg/mL (200.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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