PLX7904

Raf inhibitor

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Catalog No. A15855

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PLX7904 5mg A15855-5
$150.00
PLX7904 10mg A15855-10
$250.00
PLX7904 25mg A15855-25
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PLX7904 is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.

PLX7904

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Chemical Information

Catalog Num A15855
Actions Inhibitor
M. Wt 512.53
Formula C24H22F2N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1393465-84-3
Synonyms PB04
SMILES code N/A
Chemical Name Sulfamide, N'-?[3-?[[5-?(2-?cyclopropyl-?5-?pyrimidinyl)?-?1H-?pyrrolo[2,?3-?b]?pyridin-?3-?yl]?carbonyl]?-?2,?4-?difluorophenyl]?-?N-?ethyl-?N-?methyl-

Biological Activity

Description
PLX7904 is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Targets
Raf

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