Poziotinib

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EGFR inhibitor

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Catalog No. A13044

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Poziotinib 5mg A13044-5

Regular Price: $70.00

Special Price: $59.50

Poziotinib 10mg A13044-10

Regular Price: $100.00

Special Price: $85.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

Poziotinib

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Chemical Information

Catalog Num A13044
Actions Inhibitor
M. Wt 491.34
Formula C23H21Cl2FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1092364-38-9
Synonyms HM781-36B, NOV120101, NOV-120101, NOV 120101
SMILES code COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
Chemical Name 1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one

Biological Activity

Description
Poziotinib is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Targets
HER1 HER2 HER4
3.2 nM5.3 nM23.5 nM

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