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Ubiquitin E1 Inhibitor

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Catalog No. A13254
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Product Name Catalog No. Price
PYR-41 10mg A13254-10

Regular Price: $90.00

Special Price: $72.00

PYR-41 25mg A13254-25

Regular Price: $180.00

Special Price: $144.00

PYR-41 50mg A13254-50

Regular Price: $300.00

Special Price: $240.00

PYR-41 100mg A13254-100

Regular Price: $500.00

Special Price: $400.00

PYR-41 10mM * 1mL in DMSO A13254-10mM-D

Regular Price: $65.00

Special Price: $52.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM).


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Chemical Information

Catalog Num A13254
Actions Inhibitor
M. Wt 371.3
Formula C17H13N3O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 418805-02-4
Synonyms PYR 41, PYR41
SMILES code CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2
Chemical Name 4-[4-[(5-Nitro-2-furanyl)methylene]?-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester

Biological Activity

PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM).
Ubiquitin-activating Enzyme E1 (Cell-free assay)
<10 μM


Solubility (25°C)* In vitro DMSO 74 mg/mL (199.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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