R788 (Fostamatinib)

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Syk inhibitor

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Catalog No. A11926

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
R788 2mg A11926-2

Regular Price: $60.00

Special Price: $51.00

R788 5mg A11926-5

Regular Price: $100.00

Special Price: $85.00

R788 10mg A11926-10

Regular Price: $180.00

Special Price: $153.00

R788 25mg A11926-25

Regular Price: $400.00

Special Price: $340.00

R788 (Fostamatinib) 10mM * 1mL in DMSO A11926-10mM-D

Regular Price: $233.00

Special Price: $198.05

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.

R788 (Fostamatinib)

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Chemical Information

Catalog Num A11926
Actions Inhibitor
M. Wt 580.5
Formula C23H26FN6O9P
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 901119-35-5
Synonyms R-788
SMILES code CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
Chemical Name (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl dihydrogen phosphate

Biological Activity

Description
R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.
Targets
Syk Adenosine A3 receptor Adenosine transporter Monoamine transporter
41 nM81 nM1.84 μM2.74 μM

Solubility

Solubility (25°C) * In vitro DMSO 116 mg/mL (199.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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