Roscovitine (Seliciclib)

Roscovitine (Seliciclib) is a CDK inhibitor that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9.
Grouped product items
Product Name Price Stock Qty
Roscovitine 10mg
$65.00
In stock
Roscovitine 50mg
$150.00
In stock
Roscovitine 100mg
$200.00
In stock
Roscovitine 200mg
$300.00
In stock
Roscovitine (Seliciclib) 10mM * 1mL in DMSO
$60.00
In stock
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Adooq Products cited in reputable paper
Adooq's Roscovitine (Seliciclib) has been cited by 2 publications
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Vimal Pandey, .et al. , Scientific Reports, 2019, 9, Article number: 5012 PMID: 30899038
  • Biological Activity
    Discription Roscovitine (Seliciclib) is a CDK inhibitor that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9.
    Targets
    Target Value
    Product Information
    Catalog Num A10806
    Formula C19H26N6O
    Molecular Weight 354.5
    CAS Number 186692-46-6
    SMILES CC[C@H](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
    Synonyms CYC202, Seliciclib
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 69 mg/mL (194.67 mM)
    Water Insoluble
    Ethanol 6 mg/mL (16.92 mM)
    In vivo 1% DMSO+10% Tween 80+20% N-N-dimethylacetamide+69% PEG 400 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.21 mL 141.04 mL 282.09 mL
    0.5 mM 5.64 mL 28.21 mL 56.42 mL
    1 mM 2.82 mL 14.1 mL 28.21 mL
    5 mM 0.56 mL 2.82 mL 5.64 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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