RS-127445

Catalog No.: A11165
5-HT2B receptor antagonist

RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.

Grouped product items
Product Name Price Stock Qty
RS-127445 5mg
$40.00
In stock
RS-127445 10mg
$70.00
In stock
RS-127445 50mg
$200.00
In stock
RS-127445 100mg
$320.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's RS-127445 has been cited by 1 publications
  • Takeshi Takayanagi, .et al. , Fujita Medical Journal, 2015, 1(1), 1-5, 2015
  • Biological Activity
    Discription

    RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.

    Targets
    Target Value
    Product Information
    Catalog Num A11165
    Formula C17H16FN3
    Molecular Weight 281.33
    CAS Number 199864-87-4
    SMILES CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N
    Synonyms RS127445, MT 500, RS127,445
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 54 mg/mL (191.94 mM)
    Water Insoluble
    Ethanol 8 mg/mL (28.43 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.55 mL 177.73 mL 355.45 mL
    0.5 mM 7.11 mL 35.55 mL 71.09 mL
    1 mM 3.55 mL 17.77 mL 35.55 mL
    5 mM 0.71 mL 3.55 mL 7.11 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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