SB 334867

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OX1 receptor antagonist

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Catalog No. A12786

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SB 334867 5mg A12786-5

Regular Price: $40.00

Special Price: $34.00

SB 334867 10mg A12786-10

Regular Price: $75.00

Special Price: $63.75

SB 334867 25mg A12786-25

Regular Price: $150.00

Special Price: $127.50

SB 334867 50mg A12786-50

Regular Price: $250.00

Special Price: $212.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.

SB 334867

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Chemical Information

Catalog Num A12786
Actions Antagonist
M. Wt 319.32
Formula C17H13N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 249889-64-3
Synonyms SB334867,SB-334867
SMILES code CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4
Chemical Name N-(2-Methyl-6-benzoxazolyl)-N'-1,5-n?aphthyridin-4-yl urea

Biological Activity

Description
SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.

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