SB-674042

OX1 receptor antagonist

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Catalog No. A15233

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SB-674042 5mg A15233-5
$94.00
SB-674042 10mg A15233-10
$160.00
SB-674042 50mg A15233-50
$480.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

SB-674042

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Chemical Information

Catalog Num A15233
Actions Antagonist
M. Wt 448.51
Formula C24H21FN4O2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 483313-22-0
Synonyms SB 674042, SB674042
SMILES code CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5
Chemical Name [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl]methanone

Biological Activity

Description
SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

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