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SBE 13 HCl

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PLK inhibitor

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Catalog No. A14426

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SBE 13 HCl 10mg A14426-10

Regular Price: $80.00

Special Price: $64.00

SBE 13 HCl 25mg A14426-25

Regular Price: $160.00

Special Price: $128.00

SBE 13 HCl 50mg A14426-50

Regular Price: $300.00

Special Price: $240.00

SBE 13 HCl 10mM * 1mL in DMSO A14426-10mM-D

Regular Price: $100.00

Special Price: $80.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).

SBE 13 HCl

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Chemical Information

Catalog Num A14426
Actions Inhibitor
M. Wt 479.4
Formula C24H27ClN2O4.HC
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1052532-15-6
Synonyms SBE-13, SBE 13
SMILES code COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
Chemical Name N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxybenzeneethanamine hydrochloride

Biological Activity

Description
SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).
Targets
PLK1 PLK3 PLK2
200 pM875 nM>66 μM

Solubility

Solubility (25°C)* In vitro DMSO 95 mg/mL (198.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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