SP2509 (HCI-2509)
SP2509 is a novel histone demethylase LSD1 (KDM1A) antagonist with IC50 of 13 nM; no inhibition on MAO-A and MAO-B.
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Adooq Products cited in reputable paper
Adooq's SP2509 (HCI-2509) has been cited by 1 publications
- Ziliang Yu, .et al. , Immunol Res, 2024, May 9 PMID: 38722530
Biological Activity
| Description | SP2509 is a novel histone demethylase LSD1 (KDM1A) antagonist with IC50 of 13 nM; no inhibition on MAO-A and MAO-B. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A14443 |
|---|---|
| Formula | C19H20ClN3O5S |
| Molecular Weight | 437.9 |
| CAS Number | 1423715-09-6 |
| SMILES | CC(=C1C=C(C=CC1=O)Cl)NNC(=O)C2=CC(=CC=C2)S(=O)(=O)N3CCOCC3 |
| Synonyms | SP-2509 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 36 mg/mL (82.2 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 10% DMSO+corn oil | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.84 mL | 114.18 mL | 228.36 mL |
| 0.5 mM | 4.57 mL | 22.84 mL | 45.67 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
