Spliceostatin A

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
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Spliceostatin A 1mg
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Adooq Products cited in reputable paper
Adooq's Spliceostatin A has been cited by 8 publications
  • Arfaoui A, .et al. , EMBO Mol Med, 2019, Oct;11(10):e9930 PMID: 31476112
  • KE Mengwasser, .et al. , ‎Mol Cell, 2019, S1097-2765(18)31062-1 PMID: 30686591
  • Sahar AlShareef, .et al. , BMC Genomics, 2017, 18: 260 PMID: 28347276
  • Ling Y, .et al. , Plant J, 2017, Jan;89(2):291-309 PMID: 27664942
  • Matthew J. Hangauer, .et al. , Nature, 2017, Nov 9; 551(7679): 247-250 PMID: 29088702
  • Ji Hyun Kim, .et al. , Animal Cells and Systems, 2017, 21:1, 17-22 PMID: 30460047
  • M Tanikawa, .et al. , Oncogenesis, 2016, Dec; 5(12): e280 PMID: 27991914
  • Ji Hyun Kim, .et al. , Biochim Biophys Acta, 2016, Jun; 1863(6 Pt A): 1307-1318 PMID: 27033521
  • Biological Activity
    Discription Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
    Product Information
    Catalog Num A12700
    Formula C28H43NO8
    Molecular Weight 521.65
    CAS Number 391611-36-2
    SMILES C[C@H]1C[C@H]([C@H](O[C@H]1C/C=C(\C)/C=C/[C@@H]2[C@H]([C@@]3(C[C@@](O2)(C)OC)CO3)O)C)NC(=O)/C=C/[C@H](C)OC(=O)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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