Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events.
Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A12733
Formula
C8H5NO4S
Molecular Weight
211.19
CAS Number
19983-44-9
SMILES
C1=CC(=CC2=C1C=CS2(=O)=O)[N+](=O)[O-]
Synonyms
STAT3 Inhibitor V
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
38 mg/mL (179.93 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O
9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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