SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest.
SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest.
Targets
Target
Value
Product Information
Catalog Num
A14318
Formula
C13H11N3O2
Molecular Weight
241.25
CAS Number
377090-84-1
SMILES
COC1=CC\2=C(C=C1)NC(=O)/C2=C\C3=CN=CN3
Synonyms
SU 9516, SU-9516
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
44 mg/mL (182.38 mM)
Water
Insoluble
Ethanol
Warmed: 11 mg/mL (45.6 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: