T0901317

Catalog No.: A12652
LXR/FXR agonist
T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively
Grouped product items
Product Name Price Stock Qty
T0901317 10mg
$50.00
In stock
T0901317 25mg
$70.00
In stock
T0901317 50mg
$100.00
In stock
T0901317 100mg
$150.00
In stock
T0901317 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's T0901317 has been cited by 2 publications
  • A O Hamouda, .et al. , Eur Rev Med Pharmacol Sci, 2022, Dec;26(23):8644-8659 PMID: 36524484
  • Tian Yongsong, .et al. , J Labelled Comp Radiopharm, 2022, Feb;65(2):36-44 PMID: 34957593
  • Biological Activity
    Discription T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively
    Targets
    Target Value
    Product Information
    Catalog Num A12652
    Formula C17H12F9NO3S
    Molecular Weight 481.33
    CAS Number 293754-55-9
    SMILES C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 88 mg/mL (182.82 mM)
    Water Insoluble
    Ethanol 88 mg/mL (182.82 mM)
    In vivo 2% DMSO+35% PEG 300+5% Tween 80+ddH2O 5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.78 mL 103.88 mL 207.76 mL
    0.5 mM 4.16 mL 20.78 mL 41.55 mL
    1 mM 2.08 mL 10.39 mL 20.78 mL
    5 mM 0.42 mL 2.08 mL 4.16 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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