VER 155008

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HSP 70 inhibitor

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Catalog No. A13351

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VER 155008 10mg A13351-10
$75.00
VER 155008 25mg A13351-25
$150.00
VER 155008 50mg A13351-50
$280.00
VER 155008 100mg A13351-100
$450.00
VER 155008 10mM * 1mL in DMSO A13351-10mM-D
$85.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VER 155008 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM).

VER 155008

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Chemical Information

Catalog Num A13351
Actions Inhibitor
M. Wt 556.4
Formula C25H23Cl2N7O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1134156-31-2
Synonyms VER-155008, VER155008
SMILES code C1=CC(=CC=C1COC[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]@H](O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
Chemical Name 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile

Biological Activity

Description
VER 155008 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM).
Targets
HSP70 HSC70 GRP78
0.5 μM2.6 μM2.6 μM

Solubility

Solubility (25°C) * In vitro DMSO 36 mg/mL (198.66 mM)
Water <1 mg/mL (<1 mM)
Ethanol 36 mg/mL (198.66 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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