Voreloxin

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Catalog No. A14158

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Voreloxin 5mg A14158-5
$180.00
Voreloxin 10mg A14158-10
$300.00
Voreloxin 25mg A14158-25
$600.00
Voreloxin 10mM * 1mL in DMSO A14158-10mM-D
$236.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication

Voreloxin

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Chemical Information

Catalog Num A14158
Actions N/A
M. Wt 401.44
Formula C18H19N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 175414-77-4
Synonyms N/A
SMILES code CN[[email protected]]1CN(C[C@@H]1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O
Chemical Name 7-((3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl)-4-oxo-1-(thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid.

Biological Activity

Description
Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication

Solubility

Solubility (25°C)* In vitro DMSO 20 mg/mL heating (49.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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