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VU 0364439

GluR modulator

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Catalog No. A12664

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VU 0364439 10mg A12664-10

Regular Price: $60.00

Special Price: $48.00

VU 0364439 25mg A12664-25

Regular Price: $120.00

Special Price: $96.00

VU 0364439 50mg A12664-50

Regular Price: $200.00

Special Price: $160.00

VU 0364439 100mg A12664-100

Regular Price: $650.00

Special Price: $520.00

VU 0364439 10mM * 1mL in DMSO A12664-10mM-D

Regular Price: $84.00

Special Price: $67.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).

VU 0364439

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Chemical Information

Catalog Num A12664
Actions Modulator
M. Wt 422.29
Formula C18H13Cl2N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246086-78-1
Synonyms VU0364439,VU-0364439
SMILES code C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl
Chemical Name N-[3-Chloro-4-[[(2-chlorophenyl)ami?no]sulfonyl]phenyl]-2-pyridinecarboxamide

Biological Activity

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
19.8 nM(EC50)


Solubility (25°C)* In vitro DMSO 85 mg/mL (201.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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